Publications
2013
Van Nuffel A, Ariën KK, Stove V, Schindler M, O’Neill E, Schmökel J, Van de Walle I, Naessens E, Vanderstraeten H, Van Landeghem K, Taghon T, Pulkkinen K, Saksela K, Garcia VJ, Fackler TO, Kirchhoff F, Verhasselt B.
Primate lentiviral Nef proteins deregulate T-cell development by multiple mechanisms.
Retrovirology 10:137 (2013) doi: 10.1186/1742-4690-10-137
Pede V, Rombout A, Vermeire J, Naessens E, Vanderstraeten H, Philippé J, Verhasselt B.
Expression of ZAP-70 in CLL activates NF-κB signaling.
British Journal of Hematology, 163: 621-630 (2013) doi: 10.1111/bjh.12588
Witkowski W, Verhasselt B.
Contributions of HIV-1 Nef to immune dysregulation in HIV-infected patients: a therapeutic target?
Expert Opinion Therapeutic Targets 17: 1345-1356 (2013) doi: 10.1517/14728222.2013.830712
Pede V, Rombout A, Vermeire J, Naessens E, Mestdagh P, Robberecht N, Vanderstraeten H, Van Roy N, Vandesompele J, Speleman F, Philippé J, Verhasselt B. CLL cells respond to B-cell receptor stimulation with a microRNA/mRNA signature associated with MYC activation and cell cycle progression.
PLoS One 8, e60275 (2013) doi: 10.1371/journal.pone.0060275
Tency I, Verstraelen H, Degomme O, Verhelst R, Saerens B, Verhasselt B, Vaneechoutte M, Temmerman M.
Elevated soluble triggering receptor expressed on myeloid cells (sTREM)-1 levels in maternal serum during term and preterm labor.
PLOS ONE, 8, e56050 (2013) doi: 10.1371/journal.pone.0056050
2012
Vermeire J, Naessens E, Vanderstraeten H, Landi A, Iannucci V, Van Nuffel A, Taghon T, Pizzato M, Verhasselt B.
Quantification of reverse transcriptase activity by real-time PCR as a fast and accurate method for titration of HIV, lenti- and retroviral vectors.
PLOS ONE, 7, e50859 (2012)
Messiaen P, De Spiegelaere W, Alcami J, Vervisch K, Van Acker P, Verhasselt B, Meuwissen P, Calonge E, Gutierrez-Rodero F, Rodriguez-Martín C, Poppe B, Vogelaers D, Verhofstede C, Vandekerckhove L.
Characterization of LEDGF/p75 in vivo reveals genetic variants associated with HIV-1 disease progression.
PLOS ONE, 7, e50204 (2012)
Tency I, Verstraelen H, Kroes I, Holtappels G, Verhasselt B, Vaneechoutte M, Verhelst R, Temmerman M.
Imbalances between matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) in maternal serum during preterm labor.
PLOS ONE, 7(11):e49042 (2012)
Impens F, Timmerman E, Staes A, Moens K, Ariën KK, Verhasselt B, Vandekerckhove J, Gevaert K.
A catalogue of putative HIV-1 protease host cell substrates.
Biol Chem, 393, 915-93 (2012)
Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function.
Meuwissen PJ, Stolp B, Iannucci V, Vermeire J, Naessens E, Saksela K, Geyer M, Vanham G, Arien KK, Fackler OT, Verhasselt B.
Retrovirology 9, 34 (2012)
2011
One protein to rule them all: modulation of cell surface receptors and molecules by HIV Nef.
Landi A, Iannucci V, Van Nuffel A, Meuwissen P, Verhasselt B.
Curr HIV Res 9, 496-504 (2011)
The Nef-infectivity enigma: mechanisms of enhanced lentiviral infection.
Vermeire J, Vanbillemont G, Wojciech W, Verhasselt B.
Curr HIV Res 9, 474-489 (2011)
Editorial Nef: a notorious enigmatic factor in HIV biology.
Verhasselt B.
Curr HIV Res 9, 473 (2011)
EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells.
De Weer A, Van der Meulen J, Rondou P, Taghon T, Konrad TA, De Preter K, Mestdagh P, Van Maerken T, Van Roy N, Jeison M, Yaniv I, Cauwelier B, Noens L, Poirel HA, Vandenberghe P, Lambert F, De Paepe A, Sánchez MG, Odero M, Verhasselt B, Philippé J, Vandesompele J, Wieser R, Dastugue N, Van Vlierberghe P, Poppe B, Speleman F.
Br. J. Hematol., Article first published online: 14 MAY 2011, DOI: 10.1111/j.1365-2141.2011.08737.x
Sialoadhesin (CD169/Siglec-1) Is an endocytic receptor that allows targeted delivery of toxins and antigens to macrophages.
Delputte PL, Van Gorp H, Favoreel HW, Hoebeke I, Delrue I, Dewerchin H, Verdonck F, Verhasselt B, Cox E, Nauwynck HJ.
PLoS ONE published 16 Feb 2011 10.1371/journal.pone.0016827 (2011)
2010
A real-time polymerase chain reaction assay for rapid, sensitive, and specific quantification of the JAK2V617F mutation using a locked nucleic acid-modified oligonucleotide.
Denys B, El Housni H, Nollet F, Verhasselt B, Philippe J.
J. Mol. Diagn., 12: 512-519 (2010)
Rho GTPase Cdc42 is essential for human T cell development.
Smits K, Iannucci V, Stove V, Van Hauwe P, Naessens E, Meuwissen P, Ariën KKA, Bentahir M, Plum J, Verhasselt B.
Haematologica, 95, 367-375 (2010)
2009
Comparison of miRNA profiles of microdissected Hodgkin/Reed-Sternberg cells and Hodgkin cell lines versus CD77+ B-cells reveals a distinct subset of differentially expressed miRNAs.
Van Vlierberghe P, De Weer A, Mestdagh P, Feys T, De Preter K, De Paepe P, Lambein K, Vandesompele J, Van Roy N, Verhasselt B, Poppe B, Speleman F.
Br J Haematol, 147, 686-690 (2009).
Prognostic markers in chronic lymphocytic leukemia: a comprehensive review.
Van Bockstaele F, Verhasselt B, Philippe J.
Blood Rev, 23, 25-47 (2009).
2008
Surface-expressed viral proteins in feline infectious peritonitis virus-infected monocytes are internalized through a clathrin- and caveolae-independent pathway.
Dewerchin HL, Cornelissen E, Van Hamme E, Smits K, Verhasselt B, and Nauwynck HJ.
J. Gen. Virol., 89: 2731 – 2740 (2008).
EVI1 overexpression in t(3;17) positive AML results from juxtaposition of EVI1 to the MSI2 locus at 17q22
De Weer A, Speleman F, Cauwelier B, Van Roy N, Yigit N, Verhasselt B, De Moerloose B, Benoit Y, Noens L, Selleslag D, Lippert E, Struski S, Bastard C, De Paepe A, Van Den Berghe P, Hagemeijer A, Dastugue N, Poppe B.
Haematologica, Sep 2008; 10.3324/haematol.13192.
Clathrin- and caveolae-independent entry of feline infectious peritonitis virus in monocytes depends on dynamin.
Van Hamme E, Dewerchin HL, Cornelissen E, Verhasselt B, Nauwynck HJ.
J Gen Virol 89:2147-2156 (2008).
EVII activation in blast crisis CML due to juxtaposition to the rare 17q22 partner region as part of a 4-way variant translocation t(9;22).
De Weer A, Poppe B, Cauwelier B, Carlier A, Dierick J, Verhasselt B, Philippe J, Van Roy N, Speleman F.
BMC Cancer 8 Article Number: 193 (2008).
HIV Nef: role in pathogenesis and viral fitness
Ariën K, Verhasselt B.
Curr. HIV Res., 6, 200-208 (2008).
Efficient gene transfer in CLL by mRNA electroporation.
Van Bockstaele F, Pede V, Naessens E, Van Coppernolle S, Van Tendeloo V, Verhasselt B, Philippé J.
Leukemia, 22, 323-329 (2008)
2007
Tumor necrosis factor promotes T-cell at the expense of B-cell lymphoid development from cultured human CD34+ cord blood cells.
Smits K, De Smedt M, Naessens E, De Smet G, Stove V, Taghon T, Plum J, Verhasselt B.
Exp. Hematol., 35, 1272-1278 (2007)
A detailed inventory of DNA copy number alterations in four commonly used Hodgkin's lymphoma cell lines.
Feys T, Poppe B, De Preter K, Van Roy N, Verhasselt B, De Paepe P, De Paepe A, Speleman F.
Haematologica, 92, 913-920 (2007)
Characterization of reemerging chikungunya virus.
Sourisseau M, Schilte C, Casartelli N, Trouillet C, Guivel-Benhassine F, Rudnicka D, Sol-Foulon N, Le Roux K, Prevost MC, Fsihi H, Frenkiel MP, Blanchet F, Afonso PV, Ceccaldi PE, Ozden S, Gessain A, Schuffenecker I, Verhasselt B, Zamborlini A, Saïb A, Rey FA, Arenzana-Seisdedos F, Desprès P, Michault A, Albert ML, Schwartz O.
PLoS Pathog., 3, e89 (2007).
Lipoprotein lipase mRNA expression in whole blood is a prognostic marker in B cell chronic lymphocytic leukemia.
Van Bockstaele F, Pede V, Janssens A, Callewaert F, Offner F, Verhasselt B, Philippé J.
Clin. Chem., 53, 204-212 (2007)
Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCRbeta-HOXA rearrangement: a study of the Groupe Francophone de Cytogenetique Hematologique.
B Cauwelier, H Cave, C Gervais, M Lessard, C Barin, C Perot, J Van den Akker, F Mugneret, C Charrin, MP Pages, MJ Gregoire, P Jonveaux, M Lafage-Pochitaloff, MJ Mozzicconacci, C Terre, I Luquet, P Cornillet-Lefebvre, B Laurence, G Plessis, C Lefebvre, D Leroux, H Antoine-Poirel, C Graux, L Mauvieux, P Heimann, C Chalas, E Clappier, B Verhasselt, Y Benoit, BD Moerloose, B Poppe, N Van Roy, KD Keersmaecker, J Cools, F Sigaux, J Soulier, A Hagemeijer, AD Paepe, N Dastugue, R Berger, F Speleman.
Leukemia, 21, 121-128 (2007)
2006
EBV negative Richter's syndrome from a coexistent clone after salvage treatment with alemtuzumab in a CLL patient.
A Janssens, M Berth, P De Paepe, B Verhasselt, N Van Roy, L Noens, J Philippe, F Offner. Am J Hematol. Sep 2006;81(9):706-12.
Generation of embryonic stem cell lines from mouse blastocysts developed in vivo and in vitro: relation to Oct-4 expression.
S Tielens, B Verhasselt, J Liu, M Dhont, J Van Der Elst, M Cornelissen.
Reproduction. Jul 2006;132(1):59-66.
Kolmogorov-Smirnov statistical test for analysis of ZAP-70 expression in B-CLL, compared with quantitative PCR and IgV(H) mutation status.
F Van Bockstaele, A Janssens, A Piette, F Callewaert, V Pede, F Offner, B Verhasselt, J Philippe.
Cytometry B Clin Cytom. Jul 2006;70(4):302-8.
A sensitive in-house RT-PCR genotyping system for combined detection of plasma HIV-1 and assessment of drug resistance.
K Steegen, E Demecheleer, N De Cabooter, D Nges, M Temmerman, P Ndumbe, K Mandaliya, J Plum, and C Verhofstede
J Virol Methods, May 2006; 133(2): 137-45
Vitamin D binding protein, bone status and body composition in community-dwelling elderly men.
YE Taes, S Goemaere, G Huang, I Van Pottelbergh, D De Bacquer, B Verhasselt, C Van den Broeke, JR Delanghe, and JM Kaufman
Bone, May 2006; 38(5): 701-7.
Modelling thymic HIV-1 Nef effects.
V Stove and B Verhasselt
Curr HIV Res, Jan 2006; 4(1): 57-64.
Human transferrin G277S mutation and iron deficiency in pregnancy.
J Delanghe, H Verstraelen, I Pynaert, L Debels, Y Taes, B Verhasselt, S De Henauw, and M Temmerman
Br J Haematol, Jan 2006; 132(2): 249-50.
2005
Human Immunodeficiency Virus Nef Induces Rapid Internalization of the T-Cell Coreceptor CD8ß
Veronique Stove, Inge Van de Walle, Evelien Naessens, Elisabeth Coene, Christophe Stove, Jean Plum, and Bruno Verhasselt
J. Virol., Sep 2005; 79: 11422 - 11433 (errata Oct 2005; 79:13195).
Novel cryptic chromosomal rearrangements in childhood acute lymphoblastic leukemia detected by multiple color fluorescent in situ hybridization.
B Poppe, B Cauwelier, H Van Limbergen, N Yigit, J Philippe, B Verhasselt, A De Paepe, Y Benoit, and F Speleman
Haematologica, Sep 2005; 90(9): 1179-85
The latent HIV-1 reservoir in patients undergoing HAART: an archive of pre-HAART drug resistance
Ann Noë, Jean Plum, and Chris Verhofstede
J. Antimicrob. Chemother., Apr 2005; 55: 410 - 412.
Nasal polyps in patients with and without cystic fibrosis: a differentiation by innate markers and inflammatory mediators.
S Claeys, H Van Hoecke, G Holtappels, P Gevaert, T De Belder, B Verhasselt, P Van Cauwenberge, and C Bachert
Clin Exp Allergy, Apr 2005; 35(4): 467-72.
A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias.
F Speleman, B Cauwelier, N Dastugue, J Cools, B Verhasselt, B Poppe, N Van Roy, J Vandesompele, C Graux, A Uyttebroeck, M Boogaerts, B De Moerloose, Y Benoit, D Selleslag, J Billiet, A Robert, F Huguet, P Vandenberghe, A De Paepe, P Marynen, and A Hagemeijer
Leukemia, Mar 2005; 19(3): 358-66.
2004
Low efficacy of nevirapine (HIVNET012) in preventing perinatal HIV-1 transmission in a real-life situation.
A Quaghebeur, L Mutunga, F Mwanyumba, K Mandaliya, C Verhofstede, and M Temmerman
AIDS, Sep 2004; 18(13): 1854-6.
Macrophage mannose receptor in chronic sinus disease.
S Claeys, T De Belder, G Holtappels, P Gevaert, B Verhasselt, P Van Cauwenberge, and C Bachert
Allergy, Jun 2004; 59(6): 606-12.
The AIDS epidemic: the spread of a deadly disease in the biotech era.
A Noe, C Verhofstede, and J Plum
J Biol Regul Homeost Agents, Apr 2004; 18(2): 178-82.
Drug-Resistant Variants That Evolve During Nonsuppressive Therapy Persist in HIV-1 Infected Peripheral Blood Mononuclear Cells After Long-Term Highly Active Antiretroviral Therapy.
Chris Verhofstede, Ann Noe, Els Demecheleer, Nancy De Cabooter, Filip Van Wanzeele, Bea Van Der Gucht, Dirk Vogelaers, and Jean Plum
J Acquir Immune Defic Syndr, Mar 2004; 35(5): 473-483.
2003
Placental malaria and perinatal transmission of human immunodeficiency virus type 1.
I Inion, F Mwanyumba, P Gaillard, V Chohan, C Verhofstede, P Claeys, K Mandaliya, E Van Marck, and M Temmerman
J Infect Dis, Dec 2003; 188(11): 1675-8.
Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development
Veronique Stove, Evelien Naessens, Christophe Stove, Tomek Swigut, Jean Plum, and Bruno Verhasselt
Blood, Oct 2003; 102: 2925 - 2932.
ALK activation by the CLTC-ALK fusion is a recurrent event in large B-cell lymphoma
Pascale De Paepe, Mathijs Baens, Han van Krieken, Bruno Verhasselt, Michel Stul, Annet Simons, Bruce Poppe, Geneviève Laureys, Paul Brons, Peter Vandenberghe, Frank Speleman, Marleen Praet, Chris De Wolf-Peeters, Peter Marynen, and Iwona Wlodarska
Blood, Oct 2003; 102: 2638 - 2641.
Human beta-defensins and toll-like receptors in the upper airway.
S Claeys, T de Belder, G Holtappels, P Gevaert, B Verhasselt, P van Cauwenberge, and C Bachert
Allergy, Aug 2003; 58(8): 748-53.
Diversity of the Human Immunodeficiency Virus Type 1 (HIV-1) env Sequence after Vertical Transmission in Mother-Child Pairs Infected with HIV-1 Subtype A
Chris Verhofstede, Els Demecheleer, Nancy De Cabooter, Philippe Gaillard, Fabian Mwanyumba, Patricia Claeys, Varsha Chohan, Kishorchandra Mandaliya, Marleen Temmerman, and Jean Plum
J. Virol., Mar 2003; 77: 3050 - 3057.
Generation of transgenic T cells from human CD34+ cord blood cells.
B Verhasselt, E Naessens, and V Stove
Methods Mol Biol, Jan 2003; 215: 327-39.
2002
Active Form of Notch Imposes T Cell Fate in Human Progenitor Cells
Magda De Smedt, Katia Reynvoet, Tessa Kerre, Tom Taghon, Bruno Verhasselt, Bart Vandekerckhove, Georges Leclercq, and Jean Plum
J. Immunol., Sep 2002; 169: 3021.
Identification of Biologically Active Chemokine Isoforms from Ascitic Fluid and Elevated Levels of CCL18/Pulmonary and Activation-regulated Chemokine in Ovarian Carcinoma
Evemie Schutyser, Sofie Struyf, Paul Proost, Ghislain Opdenakker, Geneviève Laureys, Bruno Verhasselt, Lieven Peperstraete, Ignace Van de Putte, Alessandra Saccani, Paola Allavena, Alberto Mantovani, and Jo Van Damme
J. Biol. Chem., Jun 2002; 277: 24584 - 24593.
Placental inflammation and perinatal transmission of HIV-1.
F Mwanyumba, P Gaillard, I Inion, C Verhofstede, P Claeys, V Chohan, S Vansteelandt, K Mandaliya, M Praet, and M Temmerman
J Acquir Immune Defic Syndr, Mar 2002; 29(3): 262-9.
HOX-A10 regulates hematopoietic lineage commitment: evidence for a monocyte-specific transcription factor
Tom Taghon, Frank Stolz, Magda De Smedt, Maggy Cnockaert, Bruno Verhasselt, Jean Plum, and Georges Leclercq
Blood, Feb 2002; 99: 1197 - 1204.
2001
Prevalence of genotypic resistance among antiretroviral drug-naive HIV-1-infected patients in Belgium.
K Van Vaerenbergh, L Debaisieux, N De Cabooter, C Declercq, K Desmet, K Fransen, B Maes, D Marissens, K Miller, G Muyldermans, S Sprecher, L Stuyver, D Vaira, C Verhofstede, G Zissis, M Van Ranst, E De Clercq, J Desmyter, and AM Vandamme
Antivir Ther, Mar 2001; 6(1): 63-70.
Vaginal lavage with chlorhexidine during labour to reduce mother-to-child HIV transmission: clinical trial in Mombasa, Kenya.
P Gaillard, F Mwanyumba, C Verhofstede, P Claeys, V Chohan, E Goetghebeur, K Mandaliya, J Ndinya-Achola, and M Temmerman
AIDS, Feb 2001; 15(3): 389-96.
2000
Exposure to HIV-1 during delivery and mother-to-child transmission.
P Gaillard, C Verhofstede, F Mwanyumba, P Claeys, V Chohan, K Mandaliya, J Bwayo, J Plum, and M Temmerman
AIDS, Oct 2000; 14(15): 2341-8.
Efficiency of transgenic T cell generation from gene-marked cultured human CD34+ cord blood cells is determined by their maturity and the cytokines present in the culture medium.
B Verhasselt, E Naessens, M De Smedt, and J Plum
Gene Ther, May 2000; 7(10): 830-6.
Baseline HIV type 1 genotypic resistance to a newly added nucleoside analog is predictive of virologic failure of the new therapy.
K Van Vaerenbergh, K Van Laethem, E Van Wijngaerden, JC Schmit, F Schneider, L Ruiz, B Clotet, C Verhofstede, F Van Wanzeele, G Muyldermans, P Simons, L Stuyver, P Hermans, C Evans, E De Clercq, J Desmyter, and AM Vandamme
AIDS Res Hum Retroviruses, Apr 2000; 16(6): 529-37.
Blinded, multicenter quality control study for the quantification of human immunodeficiency virus type 1 RNA in plasma by the Belgian AIDS reference laboratories.
G Muyldermans, L Debaisieux, K Fransen, D Marissens, K Miller, D Vaira, AM Vandamme, AT Vandenbroucke, C Verhofstede, R Schuurman, G Zissis, and S Lauwers
Clin Microbiol Infect, Apr 2000; 6(4): 213-7.
Signals from the IL-9 Receptor Are Critical for the Early Stages of Human Intrathymic T Cell Development
Magda De Smedt, Bruno Verhasselt, Tessa Kerre, Dominique Vanhecke, Evelien Naessens, Georges Leclercq, Jean-Christophe Renauld, Jacques Van Snick, and Jean Plum
J. Immunol., Feb 2000; 164: 1761.
Human T Lymphopoiesis: In Vitro and In Vivo Study Models
J. Plum, M. De Smedt, B. Verhasselt, T. Kerre, D. Vanhecke, B. Vandekerckhove, and G. Leclercq
Ann. N.Y. Acad. Sci., Jan 2000; 917: 724.
1999
Interruption of reverse transcriptase inhibitors or a switch from reverse transcriptase to protease inhibitors resulted in a fast reappearance of virus strains with a reverse transcriptase inhibitor-sensitive genotype.
C Verhofstede, FV Wanzeele, B Van Der Gucht, N De Cabooter, and J Plum
AIDS, Dec 1999; 13(18): 2541-6.
Thymic Repopulation by CD34+ Human Cord Blood Cells After Expansion in Stroma-Free Culture
Bruno Verhasselt, Tessa Kerre, Evelien Naessens, Dominique Vanhecke, Magda De Smedt, Bart Vandekerckhove, and Jean Plum
Blood, Dec 1999; 94: 3644 - 3652.
Human Immunodeficiency Virus nef Gene Expression Affects Generation and Function of Human T Cells, But Not Dendritic Cells
Bruno Verhasselt, Evelien Naessens, Chris Verhofstede, Magda De Smedt, Sigrid Schollen, Tessa Kerre, Dominique Vanhecke, and Jean Plum
Blood, Oct 1999; 94: 2809 - 2818.
In Vitro Intrathymic Differentiation Kinetics of Human Fetal Liver CD34+CD38- Progenitors Reveals a Phenotypically Defined Dendritic/T-NK Precursor Split
Jean Plum, Magda De Smedt, Bruno Verhasselt, Fritz Offner, Tessa Kerre, Dominique Vanhecke, Georges Leclercq, and Bart Vandekerckhove
J. Immunol., Jan 1999; 162: 60.
1998
Isolation of HIV-1 RNA from plasma: evaluation of seven different methods for extraction (part two).
K Fransen, D Mortier, L Heyndrickx, C Verhofstede, W Janssens, and G van der Groen
J Virol Methods, Dec 1998; 76(1-2): 153-7.
Haptoglobin polymorphism, iron metabolism and mortality in HIV infection.
JR Delanghe, MR Langlois, JR Boelaert, J Van Acker, F Van Wanzeele, G van der Groen, R Hemmer, C Verhofstede, M De Buyzere, D De Bacquer, V Arendt, and J Plum
AIDS, Jun 1998; 12(9): 1027-32.
Retrovirally Transduced CD34++ Human Cord Blood Cells Generate T Cells Expressing High Levels of the Retroviral Encoded Green Fluorescent Protein Marker In Vitro
Bruno Verhasselt, Magda De Smedt, Rita Verhelst, Evelien Naessens, and Jean Plum
Blood, Jan 1998; 91: 431 - 440.
1997
Human thymocytes become lineage committed at an early postselection CD69+ stage, before the onset of functional maturation
D Vanhecke, B Verhasselt, M De Smedt, G Leclercq, J Plum, and B Vandekerckhove
J. Immunol., Dec 1997; 159: 5973.
Prevention of congenital toxoplasmosis in Szeged, Hungary
Z Szenasi, Z Ozsvar, E Nagy, M Jeszenszky, J Szabo, J Gellen, M Vegh, and C Verhofstede
Int. J. Epidemiol., Apr 1997; 26: 428 – 435.
MHC class II molecules are required for initiation of positive selection but not during terminal differentiation of human CD4 single positive thymocytes
D Vanhecke, B Verhasselt, M De Smedt, B De Paepe, G Leclercq, J Plum, and B Vandekerckhove
J. Immunol., Apr 1997; 158: 3730.
Line probe assay for rapid detection of drug-selected mutations in the human immunodeficiency virus type 1 reverse transcriptase gene
L Stuyver, A Wyseur, A Rombout, J Louwagie, T Scarcez, C Verhofstede, D Rimland, RF Schinazi, and R Rossau
Antimicrob. Agents Chemother., Feb 1997; 41: 284 - 291.
1996
Interleukin-7 is a critical growth factor in early human T-cell development
J Plum, M De Smedt, G Leclercq, B Verhasselt, and B Vandekerckhove
Blood, Dec 1996; 88: 4239 - 4245.
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene.
M Samson, F Libert, BJ Doranz, J Rucker, C Liesnard, CM Farber, S Saragosti, C Lapoumeroulie, J Cognaux, C Forceille, G Muyldermans, C Verhofstede, G Burtonboy, M Georges, T Imai, S Rana, Y Yi, RJ Smyth, RG Collman, RW Doms, G Vassart, and M Parmentier
Nature, Aug 1996; 382(6593): 722-5.
Isolation of HIV-1 RNA from plasma: evaluation of eight different extraction methods.
C Verhofstede, K Fransen, D Marissens, R Verhelst, G van der Groen, S Lauwers, G Zissis, and J Plum
J Virol Methods, Jul 1996; 60(2): 155-9.
1995
Differentiation to T helper cells in the thymus. Gradual acquisition of T helper cell function by CD3+CD4+ cells
D Vanhecke, B Verhasselt, V Debacker, G Leclercq, J Plum, and B Vandekerckhove
J. Immunol., Nov 1995; 155: 4711.
Case of recurrent Flavimonas oryzihabitans bacteremia associated with an implanted central venous catheter (Port-A-Cath): assessment of clonality by arbitrarily primed PCR
B Verhasselt, G Claeys, A Elaichouni, G Verschraegen, G Laureys, and M Vaneechoutte
J. Clin. Microbiol., Nov 1995; 33: 3047 - 3048.
Standardisation of primers and an algorithm for HIV-1 diagnostic PCR evaluated in patients harbouring strains of diverse geographical origin. The Belgian AIDS Reference Laboratories.
AM Vandamme, K Fransen, L Debaisieux, D Marissens, S Sprecher, D Vaira, AT Vandenbroucke, and C Verhofstede
J Virol Methods, Feb 1995; 51(2-3): 305-16.
1994
Evaluation of proviral copy number and plasma RNA level as early indicators of progression in HIV-1 infection: correlation with virological and immunological markers of disease.
C Verhofstede, S Reniers, F Van Wanzeele, and J Plum
AIDS, Oct 1994; 8(10): 1421-7.
Colorimetric quantification of urinary iron during deferoxamine therapy
B Verhasselt, J Delangle, A Verstraete, and G Leroux-Roels
Clin. Chem., Mar 1994; 40: 497 - 498.
1993
Polymerase chain reaction in the diagnosis of Toxoplasma encephalitis.
C Verhofstede, S Reniers, R Colebunders, F van Wanzeele, and J Plum
AIDS, Nov 1993; 7(11): 1539-41.
Mixed phenotype murine leukemias.
MP Defresne, B Borremans, C Verhofstede, A Peled, A Thiry, R Greimers, P Robberecht, B Nabarra, L Verschaeve, and R Hooghe
Leukemia, Aug 1993; 7(8): 1253-60.
1992
Interleukin-1 is a motility factor for human breast carcinoma cells in vitro: additive effect with interleukin-6.
B Verhasselt, J Van Damme, N van Larebeke, W Put, M Bracke, C De Potter, and M Mareel
Eur J Cell Biol, Dec 1992; 59(2): 449-57.
1991
Arrest of MCF-7 cell migration by laminin in vitro: possible mechanisms.
P Coopman, B Verhasselt, M Bracke, G De Bruyne, V Castronovo, M Sobel, JM Foidart, F Van Roy, and M Mareel
Clin Exp Metastasis, Sep 1991; 9(5): 469-84.
Hepatitis C among risk groups for HIV and hepatitis B.
S Vanderschueren, L Van Renterghem, J Plum, C Verhofstede, R Mak, and J Vincke
Int J STD AIDS, May 1991; 2(3): 185-7.
1990
Evaluation of immunoblotting for the detection of Toxoplasma gondii immunoglobulin M antibodies.
C Verhofstede, L Van Renterghem, and J Plum
Eur J Clin Microbiol Infect Dis, Nov 1990; 9(11): 835-7.
In vitro culture of chick down feather bulbi: a tool to obtain proliferating and differentiating keratinocytes in an organotypic structure.
H Beele, B Verhasselt, H Thierens, and L de Ridder
Experientia, Oct 1990; 46(10): 1053-7.
Effects of serotonin and ketanserin on the functional morphology of chick down feather bulbi in vitro.
H Beele, H Thierens, B Verhasselt, and L de Ridder
Experientia, Oct 1990; 46(10): 1057-60.
1989
The subcellular localization of the neu protein in human normal and neoplastic cells.
CR De Potter, J Quatacker, G Maertens, S Van Daele, C Pauwels, C Verhofstede, W Eechaute, and H Roels
Int J Cancer, Dec 1989; 44(6): 969-74.
Comparison of six commercial enzyme linked immunosorbent assays for detecting IgM antibodies against Toxoplasma gondii
C Verhofstede, L Van Renterghem, and J Plum
J. Clin. Pathol., Dec 1989; 42: 1285 - 1290.
1988
The infection-stage-related IgG response to Toxoplasma gondii studied by immunoblotting.
C Verhofstede, P Van Gelder, and M Rabaey
Parasitol Res, Jan 1988; 74(6): 516-20.
1987
Ability of enzyme-linked immunosorbent assays to detect early immunoglobulin G antibodies to Toxoplasma gondii.
C Verhofstede, L Sabbe, and L Van Renterghem
Eur J Clin Microbiol, Apr 1987; 6(2): 147-51.